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Anti-PCSK5 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Proprotein convertase subtilisin/kexin type 5 |
Synonyms: | hPC6, PC5, PC6, PC6A, PCSK5, Proprotein convertase 5, Proprotein convertase 6, SPC6 |
Immunogen: | Recombinant protein corresponding to Mouse PCSK5 |
Uniprot ID: | Q04592 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 800-1: 2400 | colon, kideny, lung |
Background
Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive and regulated secretory pathways. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha-integrins. May be responsible for the maturation of gastrointestinal peptides. May be involved in the cellular proliferation of adrenal cortex via the activation of growth factors.
Images
| Immunohistochemistry analysis of paraffin embedded human colon using PCSK5 (GB114694) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded rat kideny using PCSK5 (GB114694) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded mouse lung using PCSK5 (GB114694) at dilution of 1: 800 |
| Immunofluorescence of paraffin embedded human colon using PCSK5 (GB114694) at dilution of 1: 800 |
| Immunofluorescence of paraffin embedded rat colon using PCSK5 (GB114694) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
