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Anti-PDE5A/PDE5 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PDE5A rabbit polyclonal antibody |
Gene Name: | cGMP-specific 3',5'-cyclic phosphodiesterase |
Synonyms: | Pde5a, Pde5, cGMP-binding cGMP-specific phosphodiesterase, CGB-PDE, CN5A, phosphodiesterase 5A, phosphodiesterase isozyme 5, PDE5A1 |
Immunogen: | Recombinant protein corresponding to Mouse PDE5A |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 98 kDa |
Observed MW. | 105 kDa |
Uniprot ID: | O76074, Q8CG03, O54735 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, lung, skeletal muscle |
Background
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Images
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Western blot analysis of PDE5A (GB111522) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
