Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Protein disulfide-isomerase A5 |
Synonyms: | PDIA5, PDIR, Protein disulfide isomerase A5 |
Immunogen: | Recombinant protein corresponding to Mouse PDIA5 |
Uniprot ID: | Q921X9 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 60 kDa / 60 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | pancreas |
Background
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein- and non-protein-coding transcript variants.
Images
Western blot analysis of PDIA5 (GB114208) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |