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| Reactivity: | Human |
| Applications: | FCM, IC |
| Host Species: | Rat |
| Isotype: | Rat IgG1, κ |
| Clonality: | Monoclonal |
| Conjugation: | PE/TR |
| Synonyms: | Interleukin-4,IL-4,B-cell IgG differentiation factor,B-cell growth factor 1,BSF-1,IGG1 induction factor |
| Background: | IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells. |
| Gene ID: | 3565 |
| SwissProt: | P05112 |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. |
| Documents: | Please contact us to request the manual |
