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Anti-PHF17 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PHF17 rabbit polyclonal antibody |
Gene Name: | Protein Jade-1 |
Synonyms: | JADE1, KIAA1807, PHD finger protein 17, PHF17, Protein Jade 1, Jade family PHD finger 1, Gene for apoptosis and differentiation in epithelia |
Immunogen: | Recombinant protein corresponding to Mouse PHF17 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 94 kDa |
Observed MW. | 60 kDa |
Uniprot ID: | Q6ZPI0 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | kidney, liver, pancreas, heart |
Background
Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation. May also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function.
Images
 | Western blot analysis of JADE1 (GB113943) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
