Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PIP4K2 rabbit polyclonal antibody |
Gene Name: | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha |
Synonyms: | 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha, Diphosphoinositide kinase 2-alpha, PI(5)P 4-kinase type II alpha, PIP4KII-alpha, PtdIns(5)P-4-kinase isoform 2-alpha, Pip4k2a, Pip5k2a, PIP4K2 |
Immunogen: | Recombinant protein corresponding to Mouse PIP4K2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 46 kDa |
Observed MW. | 50 kDa |
Uniprot ID: | P48426, O70172, Q9R0I8 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1:500-1: 1000 | brain, spinal cord |
Background
This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. Phosphatidylinositol-5, 4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5, 4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity.
Images
Western blot analysis of Pip4k2a (GB111021) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |