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Anti-PKC beta 2 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PKC beta 2 rabbit polyclonal |
Gene Name: | Protein kinase C beta type |
Synonyms: | Prkcb, rotein Kinase C, KPCB, PKC Beta, PKC-B, PRKCB II, PRKCB2, Protein kinase C beta, Protein kinase C beta type, PKC-β2 |
Immunogen: | Recombinant protein corresponding to Mouse PKC-β2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 1200-1: 3000 | brain, cerebellum |
IF | Mouse, Rat | 1: 750-1: 1500 | brain, cerebellum |
Background
Protein kinase C (PKC) is a family of serine and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse brain using PKC-β2 (GB11833) at dilution of 1: 3000 |
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Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using PKC-β2 (GB11833) at dilution of 1: 3000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
