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Anti-PLSCR3 Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Phospholipid scramblase 3 |
Synonyms: | Plscr3, PLSCR3, phospholipid scramblase 3, Ca(2+)-dependent phospholipid scramblase 3, phospholipid |
Immunogen: | Recombinant protein corresponding to Mouse PLSCR3 |
Uniprot ID: | Q9JIZ9 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 32 kDa / 32 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | lung, uterus, brain |
ICC/IF | Mouse, Rat | 1: 100-1: 400 | NIH-3T3 |
Background
PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis.
Images
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Western blot analysis of plscr3 (GB11859) at dilution of 1: 500 |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed NIH-3T3 cells using PLSCR3(GB11859) at dilution of 1: 100-1: 400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
