Reactivity: | M |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PME-1 rabbit polyclonal |
Gene Name: | Protein phosphatase methylesterase 1 |
Synonyms: | PME-1, PME1, PPME1, PRO0750, Testicular Secretory Protein Li 39 |
Immunogen: | Recombinant protein corresponding to Mouse PME-1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: |
Product Usage Information
IHC/IF | Mouse | 1: 1000-1: 2000 | testis |
Background
This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants.
Images
Immunohistochemistry analysis of paraffin-embedded mouse testis using PME-1 (GB113355) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |