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Anti-PNPT1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PNPT1 rabbit polyclonal antibody |
Gene Name: | Polyribonucleotide nucleotidyltransferase 1, mitochondrial |
Synonyms: | 3'-5' RNA exonuclease OLD35, PNPase old-35, Polynucleotide phosphorylase 1, PNPase 1, Polynucleotide phosphorylase-like protein, Pnpt1, Pnpase |
Immunogen: | Recombinant protein corresponding to Mouse PNPT1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 86 kDa |
Observed MW. | 90 kDa |
Uniprot ID: | Q8TCS8, Q8K1R3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, kidney, skin |
Background
PNPT1 (polynucleotide phosphorylase1; also known as PNPASE) localizes in the mitochondrial intermembrane and regulates RNA import into mitochondria PNPT1 is also involved in mRNA degradation. As a type I IFN-inducible gene, PNPT1 plays an essential role in mediating IFN-mediated growth inhibition and inflammatory processes. Recently mutation in PNPT1 has been reported to cause hereditary hearing loss.
Images
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Western blot analysis of PNPT1 (GB111520) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
