Your shopping cart is empty!
Anti-POGLUT1 Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | POGLUT1 rabbit polyclonal antibody |
Gene Name: | Protein O-glucosyltransferase 1 |
Synonyms: | protein,O-glucosyltransferase Rumi homolog, Rumi, Wsnp, Poglut1, Clp46, Ktelc1, KTEL motif-containing protein 1, CAP10-like 46 kDa |
Immunogen: | Recombinant protein corresponding to Mouse POGLUT1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 46 kDa |
Observed MW. | 40 kDa |
Uniprot ID: | Q8BYB9 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 500-1: 1000 | heart |
Background
CLP46 is a KTEL motif-containing protein that belongs to the CAP10 family. The KTEL motif at the C-terminus of CLP46 is an endoplasmic reticulum (ER) retention signal which localizes the CLP46 protein to the lumen of the ER. CLP46 is thought to promote cell proliferation and is also believed to be involved with hepatic functions. The Drosophila protein rumi, a CAP10 protein and likely similar in function to CLP46, uses glucosylation to act as a Notch signaling regulator. Expressed in varying degrees in most adult tissue, CLP46 is especially abundant in the liver. CLP46 is not expressed in detectable levels in colon, thymus or small intestine. Human CLP46 shares 94% and 91% sequence similarity with its bovine and mouse homologs, respectively.
Images
| Western blot analysis of KTELC1 (GB111993) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
