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| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PYK2 rabbit polyclonal antibody |
Gene Name: | Protein-tyrosine kinase 2-beta |
Synonyms: | Ptk2b, PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK, Protein tyrosine kinase 2 beta |
Immunogen: | Recombinant protein corresponding to Mouse PYK2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: | Q9QVP9, P70600 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 400-1: 3000 | breast cancer, colon, gastric cancer, kidney, lung, ovary, small intestine |
Background
Protein tyrosine kinase 2 beta is an enzyme encoded by the PTK2B gene.
The protein is a cytoplasmic protein tyrosine kinase that is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity.
Images
 | Immunohistochemistry of paraffin embedded mouse colon using pyk2 (GB11829) at dilution of 1:1500 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse kidney using pyk2 (GB11829) at dilution of 1:1500 (400x lens) |
 | Immunohistochemistry of paraffin embedded mouse lung using pyk2 (GB11829) at dilution of 1:1500 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat lung using pyk2 (GB11829) at dilution of 1:1500 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat small intestine using pyk2 (GB11829) at dilution of 1:1500 (400x lens) |
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Immunofluorescence of paraffin embedded human breast cancer using pyk2 (GB11829) at dilution of 1:800 (400x lens) |
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Immunofluorescence of paraffin embedded human gastric cancer using pyk2 (GB11829) at dilution of 1:800 (400x lens) |
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Immunofluorescence of paraffin embedded mouse ovary using pyk2 (GB11829) at dilution of 1:800 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
