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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing human AGER.
Description:
This recombinant human adenovirus type 5 (dE1/E3) expresses advanced glycosylation end product-specific receptor (AGER, also known as RAGE) under CMV promoter.
Gene Name:
Advanced Glycosylation End Product-specific Receptor
ACCN:
BC020669
Gene ID:
177
GI Number:
18088362
Fusion Tag:
C-terminus V5 epitope tag
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
The advanced glycosylation end product receptor (AGER) encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847).
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