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Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Bone Morphogenetic Protein 2 (BMP2) under a CMV promoter. |
Description: | Bone Morphogenetic Protein 2, pre-packaged adenovirus, ready to ship and ready to use format. |
Gene: | Bone Morphogenetic Protein 2 |
NCBI Acc. #: | NM_001200 |
Gene ID: | 650 |
GI Number: | 80861484 |
Fusion Tag: | No |
Promoter: | CMV |
Titer: | 1x1010~1x1011 PFU/ml |
Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
Background: | Bone morphogenetic protein-2 (BMP2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer,which binds to its receptor. There is also a 40-45 kDa form of BMP2,as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway,TGF beta signaling pathway,and cytokine-cytokine receptor interaction. |
Documents: | Please contact us to request the manual |