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| Product Category: |
Human Adenovirus Type5 (dE1/E3) expressing Bruton Agammaglobulinemia Tyrosine Kinase (BTK). |
| Description: | Bruton Agammaglobulinemia Tyrosine Kinase, premade adenovirus, ready to ship and ready to use format. |
| Gene: | Bruton Agammaglobulinemia Tyrosine Kinase |
| NCBI Acc. #: | NM_000061 |
| Gene ID: | 695 |
| GI Number: | 4557376 |
| Fusion Tag: | C-terminus 6xHN tag |
| Promoter: | CMV |
| Titer: | 1E+10~1E+11 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | The protein encoded by BTK gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Documents: | Request a manual/MSDS |
