Adenovirus BTK-V5 (200 µl)

Product Category:

Human Adenovirus Type5 (dE1/E3) expressing Bruton Agammaglobulinemia Tyrosine Kinase (BTK).

Description:

Bruton Agammaglobulinemia Tyrosine Kinase, premade adenovirus, ready to ship and ready to use format.

Gene Name:

Bruton Agammaglobulinemia Tyrosine Kinase

ACCN:

NM_000061

Gene ID:

695

GI Number:

4557376

Fusion Tag:

C-terminus V5 epitope tag

Promoter:

CMV

Titer:

1E+10~1E+11 PFU/ml

Storage Buffer:

DMEM with 2.5% BSA, 2.5% glycerol

Background:

The protein encoded by BTK gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Documents:

Manual