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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Calpain 1, (mu/I) Large Subunit (CAPN1) under a CMV promoter.
Description:
Calpain 1, (mu/I) Large Subunit, pre-packaged adenovirus, ready to ship and ready to use format.
Gene Name:
Calpain 1, (mu/I) Large Subunit
ACCN:
BC008751
Gene ID:
823
GI Number:
14250592
Fusion Tag:
V5 epitope tag at C-terminal
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
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