Your shopping cart is empty!
| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Core-binding Factor, Runt Domain, Alpha Subunit 2; Translocated To, 1; Cyclin D-related under a CMV promoter. |
| Description: | Core-binding Factor, Runt Domain, Alpha Subunit 2; Translocated To, 1; Cyclin D-related, pre-packaged adenovirus, ready to ship and ready to use format. |
| Gene: | Core-binding Factor, Runt Domain, Alpha Subunit 2; Translocated To, 1; Cyclin D-related |
| NCBI Acc. #: | BC005850 |
| Gene ID: | 862 |
| GI Number: | 13543377 |
| Fusion Tag: | C-terminus V5 epitope tag |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | CBFA2T1 gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. |
| Documents: | Please contact us to request the manual |
