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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Carnitine Palmitoyltransferase 1A (liver) (CPT1A) under a CMV promoter.
Description:
Carnitine Palmitoyltransferase 1A (liver), pre-packaged adenovirus, ready to ship and ready to use format.
Gene Name:
Carnitine Palmitoyltransferase 1A (liver)
ACCN:
BC000185
Gene ID:
1374
GI Number:
12652864
Fusion Tag:
No
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Documents:
