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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Dual-specificity Tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B).
Description:
Dual-specificity Tyrosine-(Y)-phosphorylation Regulated Kinase 1B, pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Dual-specificity Tyrosine-(Y)-phosphorylation Regulated Kinase 1B
ACCN:
BC018751
Gene ID:
9149
GI Number:
17511802
Fusion Tag:
C-terminus V5 epitope tag
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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