Your shopping cart is empty!
Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Epidermal Growth Factor Receptor (erythroblastic Leukemia Viral (v-erb-b) Oncogene Homolog, Avian) (EGFR) under a CMV promoter.
Description:
Epidermal Growth Factor Receptor (erythroblastic Leukemia Viral (v-erb-b) Oncogene Homolog, Avian), pre-packaged adenovirus, ready to ship and ready to use format.
Gene Name:
Epidermal Growth Factor Receptor (erythroblastic Leukemia Viral (v-erb-b) Oncogene Homolog, Avian)
ACCN:
U48722
Gene ID:
1956
GI Number:
1956
Fusion Tag:
No
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
EGFR, also named as ERBB1,is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12,encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread. Mutations in this gene are associated with lung cancer.
Documents:
