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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Endoglin (Osler-Rendu-Weber Syndrome 1), under CMV promoter.
Description:
Endoglin (Osler-Rendu-Weber Syndrome 1), pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Endoglin (Osler-Rendu-Weber Syndrome 1)
ACCN:
BC014271
Gene ID:
2022
GI Number:
2022
Fusion Tag:
No
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
Documents:
