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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Estrogen Receptor 1 (ESR1) under a CMV promoter.
Description:
Estrogen Receptor 1, pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Estrogen Receptor 1
ACCN:
NM_000125
Gene ID:
2099
GI Number:
2099
Fusion Tag:
No
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
ESR1 gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.
Documents:
