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Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Fanconi Anemia, Complementation Group I (FANCI) under CMV promoter. |
Description: | Fanconi Anemia, Complementation Group I, pre-made adenovirus, ready to ship and ready to use format. |
Gene: | Fanconi Anemia, Complementation Group I |
NCBI Acc. #: | NM_018193.2 |
Gene ID: | 55215 |
GI Number: | 82830439 |
Fusion Tag: | No |
Promoter: | CMV |
Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
Background: | The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms. |
Storage: | -80°C |
Documents: | Please contact us to request the manual |