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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing FOS-like Antigen 1 (FOSL1) gene under CMV promoter. |
| Description: | FOS-like Antigen 1, pre-made adenovirus, ready to ship and ready to use format. |
| Gene: | FOS-like Antigen 1 |
| NCBI Acc. #: | NM_005438 |
| Gene ID: | 8061 |
| GI Number: | 4885242 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | The v-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. Members of the c-Fos gene family, including c-Fos, Fos B, Fra-1 and Fra-2, encode nuclear phosphoproteins that are rapidly and transiently induced by a variety of agents and function as transcriptional regulators for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers that bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites. |
| Documents: | Please contact us to request the manual |
