Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Frizzled Homolog 7 (Drosophila) (FZD7) under CMV promoter.
Summary:
Frizzled Homolog 7 (Drosophila), premade adenovirus, ready to ship and ready to use format.Promoter: CMV
Gene Name:
Frizzled Homolog 7 (Drosophila)
ACCN:
BC015915
Gene ID:
8324
GI Number:
16198468
Fusion Tag:
C-terminus V5 epitope tag
Promoter:
CMV
Titer:
1E+10 ~ 1E+11 PFU/ml
Storage Buffer:
DMEM with 2% BSA & 2.5% Glycerol
Background:
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
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