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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Human Glial Cell Derived Neurotrophic Factor (GDNF).
Description:
Pre-made adenovirus for over-expression of Human Glial Cell Derived Neurotrophic Factor (GDNF), ready to ship and ready to use format.
Gene Name:
Glial Cell Derived Neurotrophic Factor
ACCN:
NM_000514
Gene ID:
2668
GI Number:
4503974
Fusion Tag:
C-terminus V5 tag
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
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