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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing GSK3B.
Description:
premade adenovirus for over-expression of human Glycogen Synthase Kinase 3 Beta, ready to ship and ready to use format.
Gene Name:
Glycogen Synthase Kinase 3 Beta
ACCN:
BC000251
Gene ID:
2932
GI Number:
12652980
Fusion Tag:
C-terminus V5 tag
Promoter:
CMV
Titer:
1E+10~1E+11 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
The protein encoded by GSK3B gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Documents:
