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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Histone Deacetylase 1 (HDAC1).
Description:
Histone Deacetylase 1, pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Histone Deacetylase 1
ACCN:
D50405
Gene ID:
3065
GI Number:
1665722
Fusion Tag:
No
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
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