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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Histone Deacetylase 3 (HDAC3) under CMV promoter.
Description:
Histone Deacetylase 3, pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Histone Deacetylase 3
ACCN:
BC000614
Gene ID:
8841
GI Number:
12653662
Fusion Tag:
C-terminus V5 epitope tag
Promoter:
CMV
Titer:
1x1011~1x1012 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Documents:
