Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Hepatocyte Nuclear Factor 4, Alpha (HNF4A).
Description:
Hepatocyte Nuclear Factor 4, Alpha, pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Hepatocyte Nuclear Factor 4, Alpha
ACCN:
BC137539.1
Gene ID:
3172
GI Number:
187953630
Fusion Tag:
V5 Epitope Tag at C-terminal
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
The protein encoded by HNF4A gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.
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