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Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Interferon Regulatory Factor 1 under CMV promoter. |
Description: | Interferon Regulatory Factor 1, pre-made adenovirus, ready to ship and ready to use format. |
Gene: | Interferon Regulatory Factor 1 |
NCBI Acc. #: | NM_002198 |
Gene ID: | 3659 |
GI Number: | 4504720 |
Fusion Tag: | No |
Promoter: | CMV |
Titer: | 1x1010~1x1011 PFU/ml |
Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
Background: | IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppression. Diseases associated with IRF1 include gastric cancer, somatic and lung cancer. |
Documents: | Please contact us to request the manual |