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Product Category: | Human Adenovirus Type5 (dE1/E3) expressing human Kynureninase (L-kynurenine Hydrolase). |
Description: | Pre-made adenovirus for over-expression of human Kynureninase (L-kynurenine Hydrolase), ready to ship and ready to use format. |
Gene: | Kynureninase (L-kynurenine Hydrolase) |
NCBI Acc. #: | BC000879.1 |
Gene ID: | 8942 |
GI Number: | 12654128 |
Fusion Tag: | C-terminus V5 tag |
Promoter: | CMV |
Titer: | 1×1010~1×1011 PFU/ml |
Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
Background: | Kynureninase (KYBU) is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene. Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene. |
Storage: | -80°C |
Documents: | Please contact us to request the manual |