Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Lysyl Oxidase-like 2 (LOXL2) under a CMV promoter.
Description:
Lysyl Oxidase-like 2,pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Lysyl Oxidase-like 2
ACCN:
BC000594
Gene ID:
4017
GI Number:
12653632
Fusion Tag:
No
Promoter:
CMV
Titer:
1x1011~1x1012 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
The LOXL2 gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Documents: