Adenovirus MFN2 (200 μl)

Product Category:

Human Adenovirus Type5 (dE1/E3) expressing MFN2.

Description:

This recombinant human adenovirus type 5 (dE1/E3) expresses human mitofusin 2 (MFN2) under CMV promoter.

Gene Name:

Mitofusin 2

ACCN:

BC017061

Gene ID:

9927

GI Number:

9927

Fusion Tag:

C-terminus V5 epitope tag

Promoter:

CMV

Titer:

1x1010~1x1011 PFU/ml

Storage Buffer:

DMEM with 2.5% BSA, 2.5% glycerol

Background:

MFN2 gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

Documents:

Manual