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| Description: | This recombinant human adenovirus type 5 (dE1/E3) expresses human Neurogenin 1 (NEUROG1) under CMV promoter. |
| Gene: | Neurogenin 1 |
| NCBI Acc. #: | NM_006161 |
| Gene ID: | 4762 |
| GI Number: | 5453769 |
| Fusion Tag: | C-terminus V5 epitope tag |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | Neurogenin 1 is a basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis. |
| Documents: | Please contact us to request the manual |
