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Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3). |
Description: | Nuclear Receptor Subfamily 4, Group A, Member 3, pre-made adenovirus, ready to ship and ready to use format. |
Gene: | Nuclear Receptor Subfamily 4, Group A, Member 3 |
NCBI Acc. #: | NM_006981 |
Gene ID: | 8013 |
GI Number: | 11276070 |
Fusion Tag: | No |
Promoter: | CMV |
Titer: | 1x1010~1x1011 PFU/ml |
Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
Background: | NOR-1, a NR4 nerve growth factor-like receptor, has been shown to affect neuronal development, T-cell apoptosis, and cancer development. NOR-1 binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is induced rapidly but transiently by a variety of stimuli. Downregulation of NOR-1 and other NGFI-B family members is correlated with drug addiction-prone behavior of Lewis rats. Three human protein isoforms have been documented: NOR-1, NOR-1beta, and NOR-1 3' variant. |
Documents: | Please contact us to request the manual |