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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Osteoglycin (OGN) under a CMV promoter. |
| Description: | Osteoglycin (osteoinductive Factor, Mimecan), pre-packaged adenovirus, ready to ship and ready to use format. |
| Gene: | Osteoglycin (osteoinductive Factor, Mimecan) |
| NCBI Acc. #: | AL110267 |
| Gene ID: | 4969 |
| GI Number: | 5817232 |
| Fusion Tag: | C-terminus V5 epitope tag |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta. Mimecan is a small proteoglycan which contains tandem leucine-rich repeats. Mimecan is encoded by the OGN gene, a member of the small leucine-rich proteoglycan (SLRP) family of proteins. Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta (TGF-beta-1 or TGF-beta-2) and may regulate osteoblast differentiation. High expression of mimecan protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants of mimecan. Alternatively spliced transcript variants that encode mimecan have been found. |
| Documents: | Please contact us to request the manual |
