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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Parkinson Disease (autosomal Recessive, Juvenile) 2 under CMV promoter. |
| Description: | Parkinson Disease (autosomal Recessive, Juvenile) 2, pre-made adenovirus, ready to ship and ready to use format. |
| Gene: | Parkinson Disease (autosomal Recessive, Juvenile) 2, Parkin |
| NCBI Acc. #: | BC022014.2 |
| Gene ID: | 5071 |
| GI Number: | 34191069 |
| Fusion Tag: | C-terminus V5 epitope tag |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | The precise function of Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. |
| Documents: | Please contact us to request the manual |
