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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing human Peroxisome Proliferative Activated Receptor, Gamma, Coactivator 1, Alpha under a CMV promoter.
Description:
Peroxisome Proliferative Activated Receptor, Gamma, Coactivator 1, Alpha, pre-packaged adenovirus, ready to ship and ready to use format.
Gene Name:
Peroxisome Proliferative Activated Receptor, Gamma, Coactivator 1, Alpha
ACCN:
NM_013261
Gene ID:
10891
GI Number:
10891
Fusion Tag:
C-terminus V5 epitope tag
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
The protein encoded by PPARGC1A gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPAR gamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination.
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