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Product Category: | Human Adenovirus Type5 (dE1/E3) expressing posphatase and tensin homolog (PTEN, also known as BZS, MGC11227, MHAM, MMAC1, PTEN1 or TEP1) under a CMV promoter. |
Summary: | Phosphatase And Tensin Homolog (mutated In Multiple Advanced Cancers 1), premade adenovirus, ready to ship and ready to use format. |
Gene Name: | Phosphatase And Tensin Homolog (mutated In Multiple Advanced Cancers 1) |
NCBI Acc. #: | NM_000314 |
Gene ID: | 5728 |
GI Number: | 4506248 |
Fusion Tag: | No |
Promoter: | CMV |
Titer: | 1E+10 ~ 1E+11 PFU/ml |
Storage Buffer: | DMEM with 2% BSA & 2.5% Glycerol |
Background: | PTEN (also designated MMAC1), products of tumor suppressor genes,are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors,such as brain,breast,kidney and prostate cancers. PTEN is a protein tyrosine phosphatase that may terminate the signaling transduction pathways mediated by PI 3-kinase/Akt. PTEN has an apparent molecular weight of 55 kDa and it is located in the cytosol. |
Documents: | Manual |