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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Runt-related Transcription Factor 2 (RUNX2). |
| Description: | Runt-related Transcription Factor 2, pre-made adenovirus, ready to ship and ready to use format. |
| Gene: | Runt-related Transcription Factor 2 |
| NCBI Acc. #: | NM_004348.3 |
| Gene ID: | 860 |
| GI Number: | 66934968 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | RUNX2 gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. |
| Documents: | Please contact us to request the manual |
