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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Retinoid X Receptor, Alpha (RXRA).
Description:
Retinoid X Receptor, Alpha, pre-made adenovirus, ready to ship and ready to use format.
Gene Name:
Retinoid X Receptor, Alpha
ACCN:
BC110998
Gene ID:
6256
GI Number:
6256
Fusion Tag:
C-terminus V5 epitope tag
Promoter:
CMV
Titer:
1x1010~1x1011 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.
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