Adenovirus SCP2 (200 μl)

Product Category:

Human Adenovirus Type5 (dE1/E3) expressing Sterol Carrier Protein 2, under CMV promoter.

Description:

Sterol Carrier Protein 2, pre-made adenovirus, ready to ship and ready to use format.

Gene Name:

Sterol Carrier Protein 2

ACCN:

BC067108.1

Gene ID:

6342

GI Number:

45501107

Fusion Tag:

C-terminus V5 epitope tag

Promoter:

CMV

Titer:

1×1010~1×1011 PFU/ml

Storage Buffer:

DMEM with 2.5% BSA, 2.5% glycerol

Background:

The SCP2 gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

Storage:

-80°C

Documents:

Manual