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Product Category:
Human Adenovirus Type5 (dE1/E3) expressing Titin-cap (telethonin) under CMV promoter.
Description:
Titin-cap (telethonin), premade adenovirus, ready to ship and ready to use format.
Gene Name:
Titin-cap (telethonin)
ACCN:
BC012628
Gene ID:
8557
GI Number:
15215002
Fusion Tag:
C-terminus V5 epitope tag
Promoter:
CMV
Titer:
1E+10~1E+11 PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.
Documents:
