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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing human Ubiquitin-like, Containing PHD And RING Finger Domains, 1 (UHRF1). |
| Description: | Pre-made adenovirus for over-expression of human Ubiquitin-like, Containing PHD And RING Finger Domains, 1 (UHRF1), ready to ship and ready to use format. |
| Gene: | Ubiquitin-like, Containing PHD And RING Finger Domains, 1 |
| NCBI Acc. #: | BC113875 |
| Gene ID: | 29128 |
| GI Number: | 88683008 |
| Fusion Tag: | C-terminus V5 tag |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | UHRF1 gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Documents: | Please contact us to request the manual |
