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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Eukaryotic Translation Initiation Factor 5A (EIF5A) under a CMV promoter. |
| Description: | Eukaryotic Translation Initiation Factor 5A, pre-packaged adenovirus, ready to ship and ready to use format. |
| Gene: | Eukaryotic Translation Initiation Factor 5A |
| NCBI Acc. #: | BC000751 |
| Gene ID: | 1984 |
| GI Number: | 12653914 |
| Fusion Tag: | C-terminus V5 epitope tag |
| Promoter: | CMV |
| Titer: | 1×1010~1×1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of TP53/p53 and TP53/p53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts. |
| Storage: | -80°C |
| Documents: | Please contact us to request the manual |
