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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Pancreatic And Duodenal Homeobox 1 (PDX1) under CMV promoter. |
| Description: | Pancreatic And Duodenal Homeobox 1 (PDX1), pre-made adenovirus, ready to ship and ready to use format. |
| Gene: | Pancreatic And Duodenal Homeobox 1 |
| NCBI Acc. #: | BC111592 |
| Gene ID: | 3651 |
| GI Number: | 109939878 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Titer: | 1x1011~1x1012 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | The protein encoded by PDX1 gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). |
| Documents: | Please contact us to request the manual |
