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Description: | Human Adenovirus Type5 (dE1/E3) expressing mouse Receptor-interacting serine/threonine-protein kinase 3. |
Gene: | Receptor-interacting serine/threonine-protein kinase 3 |
NCBI Acc. #: | BC029210 |
Gene ID: | 56532 |
Fusion Tag: | Fusion with GFP at C-terminal |
Promoter: | CMV |
Titer: | 1E+10~1E+11 PFU/ml |
Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
Background: | The product of mRIPK3 gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. |
Documents: | Request a manual/MSDS |