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Anti-14-3-3 gamma Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | 14-3-3 gamma rabbit polyclonal antibody |
Gene Name: | 14-3-3 protein gamma |
Synonyms: | YWHAG, 14-3-3gamma, PPP1R170, tyrosine 3-monooxygenase, EIEE56, tryptophan 5-monooxygenase activation protein gamma, |
Immunogen: | Recombinant protein corresponding to Mouse 14-3-3 gamma |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 28 kDa |
Observed MW. | 32 kDa |
Uniprot ID: | P61981, P61982, P61983 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | brain, testis, lung |
Background
14-3-3 protein gamma is a protein that is encoded by the YWHAG gene. This gene product belongs to the 14-3-3 protein family which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 b, g, e, z, h, q and s. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation.
Images
 |
Western blot analysis of 14-3-3γ (GB11578) at dilution of 1: 1000 |
Storage
| Storage |
Store at -20°C for one year. Avoid repeated freeze/thaw cycles |
| Storage Buffer |
PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol. |
